GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| UVM | cis | rs703842 | 1 | rs10783847 | chr12:58196447 | TSFM | chr12:58176536-58191367:+ | -0.57 | -5.04 | 5.32E-6 | Multiple sclerosis |
| UVM | cis | rs703842 | 1 | rs10783848 | chr12:58196528 | TSFM | chr12:58176536-58191367:+ | -0.57 | -5.04 | 5.32E-6 | Multiple sclerosis |
| UVM | cis | rs11190604 | 1 | rs10786596 | chr10:102282126 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.1 | 4.38E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs11190604 | 1 | rs10786597 | chr10:102291287 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.1 | 4.38E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs11190604 | 1 | rs10786598 | chr10:102291579 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.1 | 4.38E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs2564921 | 1 | rs1078968 | chr3:53123486 | RFT1 | chr3:53122503-53164470:- | -0.37 | -5.23 | 2.68E-6 | Height |
| UVM | cis | rs568617 | 1 | rs10791830 | chr11:65661291 | SNX32 | chr11:65601410-65621170:+ | 0.61 | 5.26 | 2.4E-6 | Crohn's disease |
| UVM | cis | rs10935120 | 1 | rs10804632 | chr3:134294501 | ANAPC13 | chr3:134196547-134204865:- | 0.45 | 6.73 | 1.03E-8 | Height |
| UVM | cis | rs11190604 | 1 | rs1080698 | chr10:102295114 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.1 | 4.38E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs703842 | 1 | rs10877012 | chr12:58162085 | TSFM | chr12:58176536-58191367:+ | -0.63 | -5.76 | 3.86E-7 | Multiple sclerosis |
| UVM | cis | rs703842 | 1 | rs10877013 | chr12:58165085 | TSFM | chr12:58176536-58191367:+ | -0.57 | -5.04 | 5.32E-6 | Multiple sclerosis |
| UVM | cis | rs703842 | 1 | rs10877014 | chr12:58167661 | TSFM | chr12:58176536-58191367:+ | -0.57 | -5.04 | 5.32E-6 | Multiple sclerosis |
| UVM | cis | rs703842 | 1 | rs10877015 | chr12:58167788 | TSFM | chr12:58176536-58191367:+ | -0.57 | -5.04 | 5.32E-6 | Multiple sclerosis |
| UVM | cis | rs703842 | 1 | rs10877019 | chr12:58172929 | TSFM | chr12:58176536-58191367:+ | 0.56 | 5.21 | 2.92E-6 | Multiple sclerosis |
| UVM | cis | rs11190604 | 1 | rs10883492 | chr10:102206089 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.11 | 4.24E-6 | Palmitoleic acid (16:1n-7) plasma levels |